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2 guppys (males only is suggested) should do fine in a 2.5 gallon tank, it sounds as if you have sick fish, and on top of the tank cycling, they aren't standing much of a chance.
If it were mine, I'd work with the biospira. This is NOT a chemical, it is a natural bacteria culture in large quantity, and it DOES work. Be careful not to overdose the biospira, as this will cause problems. The packages are sold for larger quantity, so you'll have to do the math and measure it out, then shake the conatainer of biospira very very well before pouring out the dose. The excess biospira would help to cycle your 29 gallon, also... so it shouldn't be wasted.
For a short period of time I would to a .5 gallon water change daily, to ensure all waste is removed from the tank right away. With clean water and good food, your fish may show improvement rapidly. It is very possible you are also dealing with a bacteria issue in your fish, in which meds may be needed. Can you post water params for the 2.5 gallon tank? (ammonia, nitrite, nitrate, and pH) Temp? Is there a heater in the tank? Fancy guppys will need a heater to do well, especially in a tank of that size. The less water in a container, the rate of fluctuation, and temp changes regularly can stress the fish. How often is the light on? Watch the temp and see if it changes after the light has been out for an hour or 2, and if so, how much of a change?
I wouldn't give up on the 2.5 gallon tank, I have 4 of them here, and they do great. It is possible to do a lot of things with a tank that size, just be aware that because it is smaller, it may end up needing a little more maintenance than a larger tank. Evaporation rates will have more impact on a smaller tank (even 10 gallons have this problem), so you'll want to keep test kits on hand to use whenever needed. Don't get into the habit of just filling the tank with water when it evaporates because this will concentrate waste levels. Always take some water out before fillilng it up, even if it's a few cupfulls. If you work with live plants and weekly water changes, don't overpopulate the tank or overfeed it, you can get it stable enough to "top off" without worry, but I wouldn't attempt this until the tank is cycled properly.
If you can post more information on the smaller tank and a pic of the guppy, it will be much easier to help you safely.
If it were mine, I'd work with the biospira. This is NOT a chemical, it is a natural bacteria culture in large quantity, and it DOES work. Be careful not to overdose the biospira, as this will cause problems. The packages are sold for larger quantity, so you'll have to do the math and measure it out, then shake the conatainer of biospira very very well before pouring out the dose. The excess biospira would help to cycle your 29 gallon, also... so it shouldn't be wasted.
For a short period of time I would to a .5 gallon water change daily, to ensure all waste is removed from the tank right away. With clean water and good food, your fish may show improvement rapidly. It is very possible you are also dealing with a bacteria issue in your fish, in which meds may be needed. Can you post water params for the 2.5 gallon tank? (ammonia, nitrite, nitrate, and pH) Temp? Is there a heater in the tank? Fancy guppys will need a heater to do well, especially in a tank of that size. The less water in a container, the rate of fluctuation, and temp changes regularly can stress the fish. How often is the light on? Watch the temp and see if it changes after the light has been out for an hour or 2, and if so, how much of a change?
I wouldn't give up on the 2.5 gallon tank, I have 4 of them here, and they do great. It is possible to do a lot of things with a tank that size, just be aware that because it is smaller, it may end up needing a little more maintenance than a larger tank. Evaporation rates will have more impact on a smaller tank (even 10 gallons have this problem), so you'll want to keep test kits on hand to use whenever needed. Don't get into the habit of just filling the tank with water when it evaporates because this will concentrate waste levels. Always take some water out before fillilng it up, even if it's a few cupfulls. If you work with live plants and weekly water changes, don't overpopulate the tank or overfeed it, you can get it stable enough to "top off" without worry, but I wouldn't attempt this until the tank is cycled properly.
If you can post more information on the smaller tank and a pic of the guppy, it will be much easier to help you safely.