03-09-2007, 12:36 AM
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I also have three common plecos. Two of them have holes exactly like that, and they have had them for about a year to two now. Your's looks as if its bleeding though, which the medication everyone else listed would be a good start.
All three of my pelcos have the white stuff you circled in the second picture, and they have had it since I can remeber. So thats not a worry either. I think it might be dead scales or something of that nature.
Common Plecos are tough fish, and can survive basically anything you can throw at them in my experience. The largest one I own (15-16 inches) about three years ago was in a tank thats filter died for a week or two while I was on vacation. Every other fish died in that tank except for him due to about 30 ppm of ammonia. He was fine and healthy as ever when I took him out, despite the water which you couldn't see even a centimeter through.