07-31-2008, 05:13 PM
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Unfortunately, things like this are almost impossible to diagnose from just looking at the outside. Even in humans, illnesses like this wouldn't be diagnosed without blood tests or perhaps a biopsy.
I could suggest that it is a tumor, kidney enlargement disease or internal infection, but they would be just that, suggestions. While tumors cannot be treated, infection can, so I'd recommend focusing on that. Since she's still eating, you have options.
The most important thing right now is keeping up her water parameters. If you don't have a heater, float her bowl in your 55G tank, to prevent temperature fluctuations. Make sure to do 50% water changes every day, and give her plenty of places to hide.
I'd recommend feeding her Medi-Gold, which is a medicated fish food. I'm aware that it's a goldfish food, but it's got the widest spectrum of antibiotics available on the market. You can break the food up into smaller bits which she will be able to eat. Metromed and Romet B are two other options if you can't find Medi-Gold.
Otherwise, you can try treating the water, but I would try medicated food first, as it can be much more gentle on the fish and will be a good way to tell if this is something which can be treated with an antibiotic.